Development of a radionuclide-labeled monoclonal anti-CD55 antibody with theranostic potential in pleural metastatic lung cancer

Decay-accelerating factor (CD55 or DAF) inhibits complement-dependent cytotoxicity. We determined that CD55 is overexpressed in 76.47% of human non-small cell lung cancer tissue specimens. We therefore developed a lutetium-177-labeled chimeric monoclonal antibody against CD55. CD55-specific single-c...

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Detalles Bibliográficos
Autores principales: Dho, So Hee, Kim, Soo Yong, Chung, Chaeuk, Cho, Eun Ha, Lee, So-Young, Kim, Ji Young, Kim, Lark Kyun, Min, Sung-Won, Lee, Jichul, Jung, Sung Hee, Lim, Jae Cheong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997699/
https://www.ncbi.nlm.nih.gov/pubmed/29895866
http://dx.doi.org/10.1038/s41598-018-27355-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997699/
https://www.ncbi.nlm.nih.gov/pubmed/29895866
http://dx.doi.org/10.1038/s41598-018-27355-8

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