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Dropping anchor: attachment of peptidylarginine deiminase via A-LPS to secreted outer membrane vesicles of Porphyromonas gingivalis

The periodontal pathogen Porphyromonas gingivalis has been invoked in the autoimmune disease rheumatoid arthritis (RA). This association relates to the peptidylarginine deiminase of P. gingivalis (PPAD), an enzyme capable of citrullinating human proteins and potentially contributing to loss of toler...

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Detalles Bibliográficos
Autores principales: Gabarrini, Giorgio, Heida, Rick, van Ieperen, Nienke, Curtis, Mike A., van Winkelhoff, Arie Jan, van Dijl, Jan Maarten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997701/
https://www.ncbi.nlm.nih.gov/pubmed/29895934
http://dx.doi.org/10.1038/s41598-018-27223-5