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Dropping anchor: attachment of peptidylarginine deiminase via A-LPS to secreted outer membrane vesicles of Porphyromonas gingivalis
The periodontal pathogen Porphyromonas gingivalis has been invoked in the autoimmune disease rheumatoid arthritis (RA). This association relates to the peptidylarginine deiminase of P. gingivalis (PPAD), an enzyme capable of citrullinating human proteins and potentially contributing to loss of toler...
Autores principales: | Gabarrini, Giorgio, Heida, Rick, van Ieperen, Nienke, Curtis, Mike A., van Winkelhoff, Arie Jan, van Dijl, Jan Maarten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997701/ https://www.ncbi.nlm.nih.gov/pubmed/29895934 http://dx.doi.org/10.1038/s41598-018-27223-5 |
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