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Modified Newcastle Disease virus as an improved vaccine vector against Simian Immunodeficiency virus

SIV infection in macaques is a relevant animal model for HIV pathogenesis and vaccine study in humans. To design a safe and effective vaccine against HIV, we evaluated the suitability of naturally-occurring avirulent Newcastle disease virus (NDV) strains and several modified versions of NDV as vecto...

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Detalles Bibliográficos
Autores principales: Manoharan, Vinoth K., Khattar, Sunil K., LaBranche, Celia C., Montefiori, David C., Samal, Siba K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997738/
https://www.ncbi.nlm.nih.gov/pubmed/29895833
http://dx.doi.org/10.1038/s41598-018-27433-x