The crystal structure of monoacylglycerol lipase from M. tuberculosis reveals the basis for specific inhibition

Monoacylglycerol lipases (MGLs) are enzymes that hydrolyze monoacylglycerol into a free fatty acid and glycerol. Fatty acids can be used for triacylglycerol synthesis, as energy source, as building blocks for energy storage, and as precursor for membrane phospholipids. In Mycobacterium tuberculosis,...

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Detalles Bibliográficos
Autores principales: Aschauer, Philipp, Zimmermann, Robert, Breinbauer, Rolf, Pavkov-Keller, Tea, Oberer, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997763/
https://www.ncbi.nlm.nih.gov/pubmed/29895832
http://dx.doi.org/10.1038/s41598-018-27051-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997763/
https://www.ncbi.nlm.nih.gov/pubmed/29895832
http://dx.doi.org/10.1038/s41598-018-27051-7

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