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Functions of CD1d-Restricted Invariant Natural Killer T Cells in Antimicrobial Immunity and Potential Applications for Infection Control

CD1d-restricted invariant natural killer T (iNKT) cells are innate-type lymphocytes that express a T-cell receptor (TCR) containing an invariant α chain encoded by the Vα14 gene in mice and Vα24 gene in humans. These iNKT cells recognize endogenous, microbial, and synthetic glycolipid antigens prese...

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Detalles Bibliográficos
Autores principales: Kinjo, Yuki, Takatsuka, Shogo, Kitano, Naoki, Kawakubo, Shun, Abe, Masahiro, Ueno, Keigo, Miyazaki, Yoshitsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997780/
https://www.ncbi.nlm.nih.gov/pubmed/29928278
http://dx.doi.org/10.3389/fimmu.2018.01266