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Loss of Metabolic Flexibility in the Failing Heart

To maintain its high energy demand the heart is equipped with a highly complex and efficient enzymatic machinery that orchestrates ATP production using multiple energy substrates, namely fatty acids, carbohydrates (glucose and lactate), ketones and amino acids. The contribution of these individual s...

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Detalles Bibliográficos
Autores principales: Karwi, Qutuba G., Uddin, Golam M., Ho, Kim L., Lopaschuk, Gary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997788/
https://www.ncbi.nlm.nih.gov/pubmed/29928647
http://dx.doi.org/10.3389/fcvm.2018.00068