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oxLDL-mediated cellular senescence is associated with increased NADPH oxidase p47phox recruitment to caveolae
Atherosclerosis develops as a consequence of inflammation and cell senescence. In critical factors involved in the atherosclerotic changes, reactive oxygen species (ROS) generation is considered a leading cause. While NADPH oxidases, particularly NOX2, are the main sources of ROS, how they are regul...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997791/ https://www.ncbi.nlm.nih.gov/pubmed/29695496 http://dx.doi.org/10.1042/BSR20180283 |