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oxLDL-mediated cellular senescence is associated with increased NADPH oxidase p47phox recruitment to caveolae

Atherosclerosis develops as a consequence of inflammation and cell senescence. In critical factors involved in the atherosclerotic changes, reactive oxygen species (ROS) generation is considered a leading cause. While NADPH oxidases, particularly NOX2, are the main sources of ROS, how they are regul...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Bai, Yuzhi, Zhao, Xia, Ru, Jing, Kang, Ning, Tian, Tian, Tang, Liying, An, Yun, Li, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997791/
https://www.ncbi.nlm.nih.gov/pubmed/29695496
http://dx.doi.org/10.1042/BSR20180283