Are We Ready for Detecting α-Synuclein Prone to Aggregation in Patients? The Case of “Protein-Misfolding Cyclic Amplification” and “Real-Time Quaking-Induced Conversion” as Diagnostic Tools

The accumulation and deposition of α-synuclein aggregates in brain tissue is the main event in the pathogenesis of different neurodegenerative disorders grouped under the term of synucleinopathies. They include Parkinson's disease, dementia with Lewy bodies and multiple system atrophy. To date,...

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Detalles Bibliográficos
Autores principales: Paciotti, Silvia, Bellomo, Giovanni, Gatticchi, Leonardo, Parnetti, Lucilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997809/
https://www.ncbi.nlm.nih.gov/pubmed/29928254
http://dx.doi.org/10.3389/fneur.2018.00415

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997809/
https://www.ncbi.nlm.nih.gov/pubmed/29928254
http://dx.doi.org/10.3389/fneur.2018.00415

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