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Nrf2 Is a Key Regulator on Puerarin Preventing Cardiac Fibrosis and Upregulating Metabolic Enzymes UGT1A1 in Rats

Puerarin is an isoflavone isolated from Radix puerariae. Emerging evidence shown that puerarin possesses therapeutic benefits that aid in the prevention of cardiovascular diseases. In this study, we evaluated the effects of puerarin on oxidative stress and cardiac fibrosis induced by abdominal aorti...

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Detalles Bibliográficos
Autores principales: Cai, Shao-Ai, Hou, Ning, Zhao, Gan-Jian, Liu, Xia-Wen, He, Ying-Yan, Liu, Hai-Lin, Hua, Yong-Quan, Li, Li-Rong, Huang, Yin, Ou, Cai-Wen, Luo, Cheng-Feng, Chen, Min-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997811/
https://www.ncbi.nlm.nih.gov/pubmed/29928229
http://dx.doi.org/10.3389/fphar.2018.00540