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Tissue-Specific Expression of the Low-Affinity IgG Receptor, FcγRIIb, on Human Mast Cells

Immediate hypersensitivity reactions are induced by the interaction of allergens with specific IgE antibodies bound via FcεRI to mast cells and basophils. While these specific IgE antibodies are needed to trigger such reactions, not all individuals harboring IgE exhibit symptoms of allergy. The lack...

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Detalles Bibliográficos
Autores principales: Burton, Oliver T., Epp, Alexandra, Fanny, Manoussa E., Miller, Samuel J., Stranks, Amanda J., Teague, Jessica E., Clark, Rachael A., van de Rijn, Matt, Oettgen, Hans C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997819/
https://www.ncbi.nlm.nih.gov/pubmed/29928276
http://dx.doi.org/10.3389/fimmu.2018.01244