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Myeloid-Derived Suppressor Cells Specifically Suppress IFN-γ Production and Antitumor Cytotoxic Activity of Vδ2 T Cells

γδ T cells represent less than 5% of circulating T cells; they exert a potent cytotoxic function against tumor or infected cells and secrete cytokines like conventional αβ T cells. As αβ T cells γδ T cells reside in the typical T cell compartments (the lymph nodes and spleen), but are more widely di...

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Detalles Bibliográficos
Autores principales: Sacchi, Alessandra, Tumino, Nicola, Sabatini, Andrea, Cimini, Eleonora, Casetti, Rita, Bordoni, Veronica, Grassi, Germana, Agrati, Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5997821/
https://www.ncbi.nlm.nih.gov/pubmed/29928279
http://dx.doi.org/10.3389/fimmu.2018.01271