Synthesis, antimicrobial activity and conformational analysis of the class IIa bacteriocin pediocin PA-1 and analogs thereof

The antimicrobial peptide pediocin PA-1 is a class IIa bacteriocin that inhibits several clinically relevant pathogens including Listeria spp. Here we report the synthesis and characterization of whole pediocin PA-1 and novel analogs thereof using a combination of solid- and solution-phase strategie...

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Detalles Bibliográficos
Autores principales: Bédard, François, Hammami, Riadh, Zirah, Séverine, Rebuffat, Sylvie, Fliss, Ismail, Biron, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998028/
https://www.ncbi.nlm.nih.gov/pubmed/29899567
http://dx.doi.org/10.1038/s41598-018-27225-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998028/
https://www.ncbi.nlm.nih.gov/pubmed/29899567
http://dx.doi.org/10.1038/s41598-018-27225-3

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