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A parthenogenetic quasi-program causes teratoma-like tumors during aging in wild-type C. elegans

A long-standing belief is that aging (senescence) is the result of stochastic damage accumulation. Alternatively, senescent pathology may also result from late-life, wild-type gene action (i.e., antagonistic pleiotropy, as argued by Williams) leading to non-adaptive run-on of developmental programs...

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Detalles Bibliográficos
Autores principales: Wang, Hongyuan, Zhao, Yuan, Ezcurra, Marina, Benedetto, Alexandre, Gilliat, Ann F., Hellberg, Josephine, Ren, Ziyu, Galimov, Evgeniy R., Athigapanich, Trin, Girstmair, Johannes, Telford, Maximilian J., Dolphin, Colin T., Zhang, Zhizhou, Gems, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998035/
https://www.ncbi.nlm.nih.gov/pubmed/29928508
http://dx.doi.org/10.1038/s41514-018-0025-3