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Imaging EGFR and HER3 through (89)Zr-labeled MEHD7945A (Duligotuzumab)
Tumor resistance to treatment paved the way toward the development of single agent drugs that target multiple molecular signatures amplified within the malignancy. The discovered crosstalk between EGFR and HER3 as well as the role of HER3 in mediating EGFR resistance made these two receptor tyrosine...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998059/ https://www.ncbi.nlm.nih.gov/pubmed/29899472 http://dx.doi.org/10.1038/s41598-018-27454-6 |