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Imaging EGFR and HER3 through (89)Zr-labeled MEHD7945A (Duligotuzumab)

Tumor resistance to treatment paved the way toward the development of single agent drugs that target multiple molecular signatures amplified within the malignancy. The discovered crosstalk between EGFR and HER3 as well as the role of HER3 in mediating EGFR resistance made these two receptor tyrosine...

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Detalles Bibliográficos
Autores principales: McKnight, Brooke N., Kuda-Wedagedara, Akhila N. W., Sevak, Kuntal K., Abdel-Atti, Dalya, Wiesend, Wendy N., Ku, Anson, Selvakumar, Dakshnamurthy, Carlin, Sean D., Lewis, Jason S., Viola-Villegas, Nerissa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998059/
https://www.ncbi.nlm.nih.gov/pubmed/29899472
http://dx.doi.org/10.1038/s41598-018-27454-6