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GATA-4-expressing mouse bone marrow mesenchymal stem cells improve cardiac function after myocardial infarction via secreted exosomes

This study aimed to investigate whether exosomes secreted by mouse GATA-4-expressing bone marrow mesenchymal stem cells (BMSCs) could induce BMSC differentiation into myocyte precursors, decrease cardiomyocyte apoptosis, and improve cardiac function following myocardial infarction (MI). BMSCs were t...

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Detalles Bibliográficos
Autores principales: He, Ji-Gang, Li, Hong-Rong, Han, Jin-Xiu, Li, Bei-Bei, Yan, Dan, Li, Hong-Yuan, Wang, Ping, Luo, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998064/
https://www.ncbi.nlm.nih.gov/pubmed/29899566
http://dx.doi.org/10.1038/s41598-018-27435-9