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Without 1α-hydroxylation, the gene expression profile of 25(OH)D(3) treatment overlaps deeply with that of 1,25(OH)(2)D(3) in prostate cancer cells
Recently, the antiproliferative action of 1,25(OH)(2)D(3) (1,25D3), an active metabolite of vitamin D(3), in the management of prostate cancer has been argued rigorously. In this study, we found that at a physiological concentration, 25(OH)D(3) (25D3), the precursor of 1,25D3 and an inactive form of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998076/ https://www.ncbi.nlm.nih.gov/pubmed/29899561 http://dx.doi.org/10.1038/s41598-018-27441-x |