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Without 1α-hydroxylation, the gene expression profile of 25(OH)D(3) treatment overlaps deeply with that of 1,25(OH)(2)D(3) in prostate cancer cells

Recently, the antiproliferative action of 1,25(OH)(2)D(3) (1,25D3), an active metabolite of vitamin D(3), in the management of prostate cancer has been argued rigorously. In this study, we found that at a physiological concentration, 25(OH)D(3) (25D3), the precursor of 1,25D3 and an inactive form of...

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Detalles Bibliográficos
Autores principales:	Susa, Takao, Iizuka, Masayoshi, Okinaga, Hiroko, Tamamori-Adachi, Mimi, Okazaki, Tomoki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998076/ https://www.ncbi.nlm.nih.gov/pubmed/29899561 http://dx.doi.org/10.1038/s41598-018-27441-x

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