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Structural and functional analysis of mRNA export regulation by the nuclear pore complex

The nuclear pore complex (NPC) controls the passage of macromolecules between the nucleus and cytoplasm, but how the NPC directly participates in macromolecular transport remains poorly understood. In the final step of mRNA export, the DEAD-box helicase DDX19 is activated by the nucleoporins Gle1, N...

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Detalles Bibliográficos
Autores principales: Lin, Daniel H., Correia, Ana R., Cai, Sarah W., Huber, Ferdinand M., Jette, Claudia A., Hoelz, André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998080/
https://www.ncbi.nlm.nih.gov/pubmed/29899397
http://dx.doi.org/10.1038/s41467-018-04459-3