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Lung cellular senescence is independent of aging in a mouse model of COPD/emphysema

Cigarette smoke (CS) induces lung cellular senescence that plays an important role in the pathogenesis of chronic obstructive pulmonary disease (COPD). How aging influences cellular senescence and other molecular hallmarks, and increases the risk of CS-induced damage remains unknown. We hypothesized...

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Detalles Bibliográficos
Autores principales: Rashid, Kahkashan, Sundar, Isaac K., Gerloff, Janice, Li, Dongmei, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998122/
https://www.ncbi.nlm.nih.gov/pubmed/29899396
http://dx.doi.org/10.1038/s41598-018-27209-3