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Assigning biological function using hidden signatures in cystine-stabilized peptide sequences

Cystine-stabilized peptides have great utility as they naturally block ion channels, inhibit acetylcholine receptors, or inactivate microbes. However, only a tiny fraction of these peptides has been characterized. Exploration for novel peptides most efficiently starts with the identification of cand...

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Detalles Bibliográficos
Autores principales: Islam, S. M. Ashiqul, Kearney, Christopher Michel, Baker, Erich J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998126/
https://www.ncbi.nlm.nih.gov/pubmed/29899538
http://dx.doi.org/10.1038/s41598-018-27177-8