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FNDC4 Inhibits RANKL-Induced Osteoclast Formation by Suppressing NF-κB Activation and CXCL10 Expression

FNDC4 acts as an anti-inflammatory factor on macrophages and improves mouse model of induced colitis. Considering osteoclast formation is characterized by the activation of inflammation-related pathways, we thus speculated that FNDC4 may play a pivotal role in this process. RT-qPCR analysis was perf...

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Detalles Bibliográficos
Autores principales: Lv, Zheng-tao, Liang, Shuang, Chen, Kun, Zhang, Jia-ming, Cheng, Peng, Guo, Jia-chao, Yang, Qing, Zhou, Chen-he, Liao, Hui, Chen, An-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998196/
https://www.ncbi.nlm.nih.gov/pubmed/29977911
http://dx.doi.org/10.1155/2018/3936257