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UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling

Neural stem cell (NSC) proliferation and differentiation in the developing brain is a complex process precisely regulated by intrinsic and extrinsic signals. Although epigenetic modification has been reportedly involved in the regulation of the cerebral cortex, whether UTX, an H3K27me3 demethylase,...

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Detalles Bibliográficos
Autores principales: Lei, Xuepei, Jiao, Jianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998300/
https://www.ncbi.nlm.nih.gov/pubmed/29551674
http://dx.doi.org/10.1016/j.stemcr.2018.02.008