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CD73 Regulates Stemness and Epithelial-Mesenchymal Transition in Ovarian Cancer-Initiating Cells

Cancer-initiating cells (CICs) have been implicated in tumor development and aggressiveness. In ovarian carcinoma (OC), CICs drive tumor formation, dissemination, and recurrence, as well as drug resistance, thus accounting for the high death-to-incidence ratio of this neoplasm. However, the molecula...

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Detalles Bibliográficos
Autores principales: Lupia, Michela, Angiolini, Francesca, Bertalot, Giovanni, Freddi, Stefano, Sachsenmeier, Kris F., Chisci, Elisa, Kutryb-Zajac, Barbara, Confalonieri, Stefano, Smolenski, Ryszard T., Giovannoni, Roberto, Colombo, Nicoletta, Bianchi, Fabrizio, Cavallaro, Ugo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998305/
https://www.ncbi.nlm.nih.gov/pubmed/29551673
http://dx.doi.org/10.1016/j.stemcr.2018.02.009