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Dietary Uridine Decreases Tumorigenesis in the Apc(Min/+) Model of Intestinal Cancer

BACKGROUND: Dietary deoxyuridine and uridine have been shown to have opposing effects on neural tube defect (NTD) incidence in the serine hydroxymethyltransferase 1 (Shmt1(+/)(–)) mouse model of folate-responsive NTDs, which are mediated by changes in de novo thymidylate biosynthesis. Alterations in...

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Detalles Bibliográficos
Autores principales: Field, Martha S, Lan, Xu, Stover, Denise M, Stover, Patrick J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998365/
https://www.ncbi.nlm.nih.gov/pubmed/29955725
http://dx.doi.org/10.1093/cdn/nzy013