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Dietary Uridine Decreases Tumorigenesis in the Apc(Min/+) Model of Intestinal Cancer
BACKGROUND: Dietary deoxyuridine and uridine have been shown to have opposing effects on neural tube defect (NTD) incidence in the serine hydroxymethyltransferase 1 (Shmt1(+/)(–)) mouse model of folate-responsive NTDs, which are mediated by changes in de novo thymidylate biosynthesis. Alterations in...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998365/ https://www.ncbi.nlm.nih.gov/pubmed/29955725 http://dx.doi.org/10.1093/cdn/nzy013 |