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Dietary Uridine Decreases Tumorigenesis in the Apc(Min/+) Model of Intestinal Cancer

BACKGROUND: Dietary deoxyuridine and uridine have been shown to have opposing effects on neural tube defect (NTD) incidence in the serine hydroxymethyltransferase 1 (Shmt1(+/)(–)) mouse model of folate-responsive NTDs, which are mediated by changes in de novo thymidylate biosynthesis. Alterations in...

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Detalles Bibliográficos
Autores principales:	Field, Martha S, Lan, Xu, Stover, Denise M, Stover, Patrick J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998365/ https://www.ncbi.nlm.nih.gov/pubmed/29955725 http://dx.doi.org/10.1093/cdn/nzy013

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