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Interaction between a MAPT variant causing frontotemporal dementia and mutant APP affects axonal transport

In Alzheimer's disease, many indicators point to a central role for poor axonal transport, but the potential for stimulating axonal transport to alleviate the disease remains largely untested. Previously, we reported enhanced anterograde axonal transport of mitochondria in 8- to 11-month-old MA...

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Detalles Bibliográficos
Autores principales: Adalbert, Robert, Milde, Stefan, Durrant, Claire, Ando, Kunie, Stygelbout, Virginie, Yilmaz, Zehra, Gould, Stacey, Brion, Jean-Pierre, Coleman, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998378/
https://www.ncbi.nlm.nih.gov/pubmed/29729423
http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.033