Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice

Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction of cross-reactive and at the same time neutra...

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Detalles Bibliográficos
Autores principales: Krapchev, Vasil B., Rychłowska, Malgorzata, Chmielewska, Alicja, Zimmer, Karolina, Patel, Arvind H., Bieńkowska-Szewczyk, Krystyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998380/
https://www.ncbi.nlm.nih.gov/pubmed/29631174
http://dx.doi.org/10.1016/j.virol.2018.03.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998380/
https://www.ncbi.nlm.nih.gov/pubmed/29631174
http://dx.doi.org/10.1016/j.virol.2018.03.026

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