Conditional deletion of Id2 or Notch1 in oligodendrocyte progenitor cells does not ameliorate disease outcome in SOD1(G93A) mice

Oligodendrocytes are essential for structural and trophic support of motor axons. Their impairment has been implicated in amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder of motor neurons. Oligodendrocyte progenitor cells fail to differentiate into mature oligodendrocytes and thereb...

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Detalles Bibliográficos
Autores principales: Eykens, Caroline, Nonneman, Annelies, Jensen, Cathy, Iavarone, Antonio, Van Damme, Philip, Van Den Bosch, Ludo, Robberecht, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998381/
https://www.ncbi.nlm.nih.gov/pubmed/29689424
http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998381/
https://www.ncbi.nlm.nih.gov/pubmed/29689424
http://dx.doi.org/10.1016/j.neurobiolaging.2018.03.026

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