Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi

BACKGROUND: The Toxicological Priority Index (ToxPi) is a method for prioritization and profiling of chemicals that integrates data from diverse sources. However, individual data sources (“assays”), such as in vitro bioassays or in vivo study endpoints, often feature sections of missing data, wherei...

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Detalles Bibliográficos
Autores principales: To, Kimberly T., Fry, Rebecca C., Reif, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998548/
https://www.ncbi.nlm.nih.gov/pubmed/29942350
http://dx.doi.org/10.1186/s13040-018-0169-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998548/
https://www.ncbi.nlm.nih.gov/pubmed/29942350
http://dx.doi.org/10.1186/s13040-018-0169-5

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