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Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi
BACKGROUND: The Toxicological Priority Index (ToxPi) is a method for prioritization and profiling of chemicals that integrates data from diverse sources. However, individual data sources (“assays”), such as in vitro bioassays or in vivo study endpoints, often feature sections of missing data, wherei...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998548/ https://www.ncbi.nlm.nih.gov/pubmed/29942350 http://dx.doi.org/10.1186/s13040-018-0169-5 |