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Reintroducing testosterone in the db/db mouse partially restores normal glucose metabolism and insulin resistance in a leptin-independent manner

BACKGROUND: Testosterone signals through the androgen receptor (AR) and AR knockout mice develop obesity, suggesting a functional association between AR and leptin signaling. Furthermore, physiological blood concentrations of testosterone have been found to inhibit the development of arteriosclerosi...

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Detalles Bibliográficos
Autores principales:	Yabiku, Koichi, Nakamoto, Keiko, Tokushige, Akihiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998571/ https://www.ncbi.nlm.nih.gov/pubmed/29895265 http://dx.doi.org/10.1186/s12902-018-0266-y

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