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Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells

BACKGROUND: Arsenic trioxide (As(2)O(3)), a drug that has been used in China for approximately two thousand years, induces cell death in a variety of cancer cell types, including neuroblastoma (NB). The tyrosine kinase receptor (Trk) family comprises three members, namely TrkA, TrkB and TrkC. Variou...

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Detalles Bibliográficos
Autores principales: Xiong, Xilin, Li, Yang, Liu, Ling, Qi, Kai, Zhang, Chi, Chen, Yueqin, Fang, Jianpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998579/
https://www.ncbi.nlm.nih.gov/pubmed/29898774
http://dx.doi.org/10.1186/s40659-018-0167-6