Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

OBJECTIVE: Spinal muscular atrophy (SMA) results from insufficient levels of the survival motor neuron (SMN) protein. Drosophila is conducive to large-scale genetic-modifier screens which can reveal novel pathways underpinning the disease mechanism. We tested the ability of a large collection of gen...

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Detalles Bibliográficos
Autores principales: Aquilina, Beppe, Cauchi, Ruben J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998591/
https://www.ncbi.nlm.nih.gov/pubmed/29895323
http://dx.doi.org/10.1186/s13104-018-3496-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998591/
https://www.ncbi.nlm.nih.gov/pubmed/29895323
http://dx.doi.org/10.1186/s13104-018-3496-1

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