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Genetic screen identifies a requirement for SMN in mRNA localisation within the Drosophila oocyte

OBJECTIVE: Spinal muscular atrophy (SMA) results from insufficient levels of the survival motor neuron (SMN) protein. Drosophila is conducive to large-scale genetic-modifier screens which can reveal novel pathways underpinning the disease mechanism. We tested the ability of a large collection of gen...

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Detalles Bibliográficos
Autores principales:	Aquilina, Beppe, Cauchi, Ruben J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Note
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998591/ https://www.ncbi.nlm.nih.gov/pubmed/29895323 http://dx.doi.org/10.1186/s13104-018-3496-1

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