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PLAG1 and USF2 Co-regulate Expression of Musashi-2 in Human Hematopoietic Stem and Progenitor Cells

MSI2, which is expressed predominantly in hematopoietic stem and progenitor cells (HSPCs), enforces HSPC expansion when overexpressed and is upregulated in myeloid leukemias, indicating its regulated transcription is critical to balanced self-renewal and leukemia restraint. Despite this, little is u...

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Detalles Bibliográficos
Autores principales: Belew, Muluken S., Bhatia, Sonam, Keyvani Chahi, Ava, Rentas, Stefan, Draper, Jonathan S., Hope, Kristin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998603/
https://www.ncbi.nlm.nih.gov/pubmed/29641991
http://dx.doi.org/10.1016/j.stemcr.2018.03.006