Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia

The derivation of microglia from human stem cells provides systems for understanding microglial biology and enables functional studies of disease-causing mutations. We describe a robust method for the derivation of human microglia from stem cells, which are phenotypically and functionally comparable...

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Detalles Bibliográficos
Autores principales: Brownjohn, Philip W., Smith, James, Solanki, Ravi, Lohmann, Ebba, Houlden, Henry, Hardy, John, Dietmann, Sabine, Livesey, Frederick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998752/
https://www.ncbi.nlm.nih.gov/pubmed/29606617
http://dx.doi.org/10.1016/j.stemcr.2018.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998752/
https://www.ncbi.nlm.nih.gov/pubmed/29606617
http://dx.doi.org/10.1016/j.stemcr.2018.03.003

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