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Functional Studies of Missense TREM2 Mutations in Human Stem Cell-Derived Microglia

The derivation of microglia from human stem cells provides systems for understanding microglial biology and enables functional studies of disease-causing mutations. We describe a robust method for the derivation of human microglia from stem cells, which are phenotypically and functionally comparable...

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Detalles Bibliográficos
Autores principales:	Brownjohn, Philip W., Smith, James, Solanki, Ravi, Lohmann, Ebba, Houlden, Henry, Hardy, John, Dietmann, Sabine, Livesey, Frederick J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998752/ https://www.ncbi.nlm.nih.gov/pubmed/29606617 http://dx.doi.org/10.1016/j.stemcr.2018.03.003

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