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Identification of drug-target interaction by a random walk with restart method on an interactome network

BACKGROUND: Identification of drug-target interactions acts as a key role in drug discovery. However, identifying drug-target interactions via in-vitro, in-vivo experiments are very laborious, time-consuming. Thus, predicting drug-target interactions by using computational approaches is a good alter...

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Detalles Bibliográficos
Autores principales: Lee, Ingoo, Nam, Hojung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998759/
https://www.ncbi.nlm.nih.gov/pubmed/29897326
http://dx.doi.org/10.1186/s12859-018-2199-x