In silico prediction of potential chemical reactions mediated by human enzymes

BACKGROUND: Administered drugs are often converted into an ineffective or activated form by enzymes in our body. Conventional in silico prediction approaches focused on therapeutically important enzymes such as CYP450. However, there are more than thousands of different cellular enzymes that potenti...

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Detalles Bibliográficos
Autores principales: Yu, Myeong-Sang, Lee, Hyang-Mi, Park, Aaron, Park, Chungoo, Ceong, Hyithaek, Rhee, Ki-Hyeong, Na, Dokyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998764/
https://www.ncbi.nlm.nih.gov/pubmed/29897324
http://dx.doi.org/10.1186/s12859-018-2194-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998764/
https://www.ncbi.nlm.nih.gov/pubmed/29897324
http://dx.doi.org/10.1186/s12859-018-2194-2

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