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Pathway-based approach using hierarchical components of rare variants to analyze multiple phenotypes
BACKGROUND: As one possible solution to the “missing heritability” problem, many methods have been proposed that apply pathway-based analyses, using rare variants that are detected by next generation sequencing technology. However, while a number of methods for pathway-based rare-variant analysis of...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998880/ https://www.ncbi.nlm.nih.gov/pubmed/29745849 http://dx.doi.org/10.1186/s12859-018-2066-9 |