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A Critical Role of TET1/2 Proteins in Cell-Cycle Progression of Trophoblast Stem Cells

The ten-eleven translocation (TET) proteins are well known for their role in maintaining naive pluripotency of embryonic stem cells. Here, we demonstrate that, jointly, TET1 and TET2 also safeguard the self-renewal potential of trophoblast stem cells (TSCs) and have partially redundant roles in main...

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Detalles Bibliográficos
Autores principales: Chrysanthou, Stephanie, Senner, Claire E., Woods, Laura, Fineberg, Elena, Okkenhaug, Hanneke, Burge, Sarah, Perez-Garcia, Vicente, Hemberger, Myriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998911/
https://www.ncbi.nlm.nih.gov/pubmed/29576538
http://dx.doi.org/10.1016/j.stemcr.2018.02.014