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RIPK3/MLKL-Mediated Neuronal Necroptosis Modulates the M1/M2 Polarization of Microglia/Macrophages in the Ischemic Cortex

Cell death and subsequent inflammation are 2 key pathological changes occurring in cerebral ischemia. Active microglia/macrophages play a double-edged role depending on the balance of their M1/M2 phenotypes. Necrosis is the predominant type of cell death following ischemia. However, how necrotic cel...

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Detalles Bibliográficos
Autores principales: Yang, Jiping, Zhao, Youyi, Zhang, Li, Fan, Hong, Qi, Chuchu, Zhang, Kun, Liu, Xinyu, Fei, Lin, Chen, Siwei, Wang, Mengmeng, Kuang, Fang, Wang, Yazhou, Wu, Shengxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5998990/
https://www.ncbi.nlm.nih.gov/pubmed/29746630
http://dx.doi.org/10.1093/cercor/bhy089