Hypothalamic stem cells control aging speed partly through exosomal miRNAs

Hypothalamic control of aging was recently proposed, but the responsible mechanisms still remain unclear. Here, following the observation that aging of mice started with a substantial loss of hypothalamic stem/progenitor cells that co-express Sox2 and Bmi1, we developed several mouse models with abl...

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Detalles Bibliográficos
Autores principales: Zhang, Yalin, Kim, Min Soo, Jia, Baosen, Yan, Jingqi, Zuniga-Hertz, Juan Pablo, Han, Cheng, Cai, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999038/
https://www.ncbi.nlm.nih.gov/pubmed/28746310
http://dx.doi.org/10.1038/nature23282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999038/
https://www.ncbi.nlm.nih.gov/pubmed/28746310
http://dx.doi.org/10.1038/nature23282

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