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PD-1/PD-L1 regulates Treg differentiation in pregnancy-induced hypertension

Pregnancy-induced hypertension (PIH) causes significant maternal and fetal morbidity and mortality. A decreased number of regulatory T (Treg) cells is associated with the pathogenesis of PIH. The programmed cell death-1 (PD-1)/PD-ligand 1 (PD-L1) pathway is critical to normal pregnancy (NP) by promo...

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Detalles Bibliográficos
Autores principales: Jiang, Lai, Tang, Chaoliang, Gong, Yanping, Liu, Yujie, Rao, Jie, Chen, Suyu, Qu, Wanjun, Wu, Dabao, Lei, Lei, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999066/
https://www.ncbi.nlm.nih.gov/pubmed/29846432
http://dx.doi.org/10.1590/1414-431X20187334