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Computational study on a puzzle in the biosynthetic pathway of anthocyanin: Why is an enzymatic oxidation/ reduction process required for a simple tautomerization?

In the late stage of anthocyanin biosynthesis, dihydroflavonol reductase (DFR) and anthocyanidin synthase (ANS) mediate a formal tautomerization. However, such oxidation/reduction process requires high energy and appears to be unnecessary, as the oxidation state does not change during the transforma...

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Detalles Bibliográficos
Autores principales: Sato, Hajime, Wang, Chao, Yamazaki, Mami, Saito, Kazuki, Uchiyama, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999093/
https://www.ncbi.nlm.nih.gov/pubmed/29897974
http://dx.doi.org/10.1371/journal.pone.0198944