Four-dimensional, dynamic mosaicism is a hallmark of normal human skin that permits mapping of the organization and patterning of human epidermis during terminal differentiation

Recent findings of mosaicism (DNA sequence variation) challenge the dogma that each person has a stable genetic constitution. Copy number variations, point mutations and chromosome abnormalities in normal or diseased tissues have been described. We studied normal skin mosaicism of a single nucleotid...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Yun, Masaki, Taro, Khan, Sikandar G., Tamura, Deborah, Kuschal, Christiane, Rogers, Megan, DiGiovanna, John J., Kraemer, Kenneth H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999106/
https://www.ncbi.nlm.nih.gov/pubmed/29897937
http://dx.doi.org/10.1371/journal.pone.0198011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999106/
https://www.ncbi.nlm.nih.gov/pubmed/29897937
http://dx.doi.org/10.1371/journal.pone.0198011

Ejemplares similares