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Four-dimensional, dynamic mosaicism is a hallmark of normal human skin that permits mapping of the organization and patterning of human epidermis during terminal differentiation
Recent findings of mosaicism (DNA sequence variation) challenge the dogma that each person has a stable genetic constitution. Copy number variations, point mutations and chromosome abnormalities in normal or diseased tissues have been described. We studied normal skin mosaicism of a single nucleotid...
Autores principales: | Wang, Yun, Masaki, Taro, Khan, Sikandar G., Tamura, Deborah, Kuschal, Christiane, Rogers, Megan, DiGiovanna, John J., Kraemer, Kenneth H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999106/ https://www.ncbi.nlm.nih.gov/pubmed/29897937 http://dx.doi.org/10.1371/journal.pone.0198011 |
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