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Anti-tumor activity of phenoxybenzamine and its inhibition of histone deacetylases

The principal finding from this study was the recognition that the α-adrenergic antagonist, phenoxybenzamine, possesses histone deacetylase inhibitory activity. Phenoxybenzamine is approved by the United States Food and Drug Administration for the treatment of hypertensive crises associated with tum...

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Detalles Bibliográficos
Autor principal: Inchiosa, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999115/
https://www.ncbi.nlm.nih.gov/pubmed/29897996
http://dx.doi.org/10.1371/journal.pone.0198514